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Structural Biology Using Electrons and X-rays
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  • Structural Biology Using Electrons and X-rays
ID: 177603
Michael F Moody
Wycofany

Structural Biology Using Electrons and X-rays is the perfect book to provide advanced undergraduates or graduate students with an accessible introduction to the two major diffraction-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray crystallography in a coherent survey of fundamental principles. Starting with Fourier transforms and progressing through optics and imaging principles, symmetry and three-dimensional reconstruction theory, Structural Biology Using Electrons and X-rays ends in an account of the latest methods adapted to crystals, helices, viral heads, and single particles.



*Emphasis on common principles underlying all diffraction-based methods


*Thorough grounding in theory requires understanding of only simple algebra


*Visual representations and explanations of challenging content


*Mathematical detail offered in short-course form to parallel the text



Part I: Fourier Transforms


1. Overview


2. Correlations & Convolutions


3. Fourier Fundamentals


4. Digital Fourier Transforms


5. Filters


6. Two-Dimensional FTs



Part II: Optics


7. Microscopy with Rays


8. Waves


9. Wave Imaging



Part III: Further Mathematical Methods/General Aspects


10. Symmetry


11. Statistics & Matrices


12. The Third Dimension



Part IV: Image Analysis/Structure Determination


13. Special Symmetries


14. Crystalline Sheets


15. Helices


16. Icosahedral Particles


17. Unsymmetrical ("Single") Particles


18. Distortion Correction


19. FT Mathematics


20. Elementary Matrices

177603

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