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Structural Biology Using Electrons and X-rays
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Structural Biology Using Electrons and X-rays is the perfect book to provide advanced diploma-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray crystallography in a coherent survey of fundamental principles. Starting with Fourier transforms and progressing through optics and imaging Principles, symmetry and three-dimensional reconstruction theory, Structural Biology Using Electrons and X-rays ends in an account of the latest methods adapted this crystals, helices, viral heads, and single particles.
* Emphasis on common principles underlying all diffraction-based methods
* Thorough grounding in theory requires a simple algebra
* Visual representations and explanations of challenging content
* Mathematical detail offered in short-course forms to the parallel text
Part I: Fourier Transforms
1. Overview
2. Correlations & Convolutions
3. Fourier Fundamentals
4. Digital Fourier Transforms
5. Filters
6. Two-Dimensional FTs
Part II: Optics
7. Microscopy with Rays
8. Waves
9. Wave Imaging
Part III: Further Mathematical Methods / General Aspects
10. Symmetry
11. Statistics & Matrices
12. The Third Dimension
Part IV: Image Analysis / Structure Determination
13. Special Symmetries
14. Crystalline Sheets
15. Helices
16. Icosahedral Particles
17. Unsymmetrical ("Single") Particles
18. Distortion Correction
19. FT Mathematics
20. Elementary Matrices
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