Cytokine Reference, Two-Volume Set (Institutional Version)

The Cytokine Reference is the ultimate defense of processes in the role of cytokines in host defense processes. With specific cytokines, including chemokines, growth factors and neuropeptides, cytokine genes, proteins, cell sources, activities, receptors, signal transduction receptor, gene activation, pathophysiology, therapeutics and techniques. This encyclopedic reference is written in a panel of global experts and diagrams. This book / online bundle consists of a two-volume print set, plus a regularly updated and searchable Online Database.
Cytokines are produced by the bacteria, tumors, and traumas. This publication and the database will need to be informed about this ever-expanding field.

Key Features
* Online extensively-linked database is very functional in a variety of ways - by cytokine, by cell type, or by disease
* Online version offers freshly updated entries and additions of new insights
* Print version has approximately 2500 pages of information about the cytokines and other mediators of host defense
* Contains over 175 chapters contributed by international experts and edited by 6 world renowned scientists
* Online database allows you to access the maze of inter-relationships
* Online version includes full color diagrams and sequences for online databases, including MEDLINE, PDB, SWISSPRO, and GenBank
* Every cytokine or receptor chapter uses the very structured subheadings, complete, comprehensive, and easy to find

Preface.
Dedication.
Contributors.
Volume I:
overview:
Introduction to the Role of Cytokines in Innate Host Defense and Adaptive Immunity, JJ Oppenheim and M. Feldmann .
Cytokine-Receptor Signaling at the Structural Level, RM Stroud, S. LaPorte and JA Wells .
Cytokines and Disease, M. Feldmann and FM Brennan .
Cytokine Assays, DG Remick and TL Whiteside .
Cytokine Standardization, RC Thorpe, AR Mire-Sluis and M. Wadhwa .
The Immunomodulating Interleukins:
Cytokines and the Immune System, SK Durum
TH1 / TH2 Interleukins, S. Romagnani .
IL-2, KA Smith .
IL-4, AD Keegan .
IL-7, H. Spits .
IL-9, J.-C. Renauld .
IL-10, R. de Waal Malefyt .
IL-12, C. Esche, MR Shurin and MT Lotze .
IL-13, ANJ McKenzie and DJ Matthews .
IL-15, TA Waldmann and Y. Tagaya .
IL-16, DM Center, H. Kornfeld and WW Cruikshank .
IL-17, S. Lebecque, F. Fossiez and E. Bates .
Growth Hormone, S. Chappel and W. Murphy .
Prolactin, H. Rui .
Parapox (Orf Virus) IL-10 Homolog, G. McFadden and R. Moyer .
The IL-1 Family:
Proinflammatory Cytokines, M. Feldmann and J. Saklatvala .
IL-1- alpha , CA Dinarello .
IL-1Ra, D. Burger and J.-M. Dayer .
IL-18, H. Okamura, H. Tsutsui, S.-i. Kashiwamura, T. Yoshimoto and K. Nakanishi .
IL-1- beta , CA Dinarello .
The TNF Family:
TNF Ligand and TNF / NGF Receptor Families, D. Wallach .
TNF alpha , BB Aggarwal, A. Samanta and M. Feldmann .
Lymphotoxin alpha and beta , N. Ruddle and CF Ware .
Fas Ligand, S. Nagata .
CD40 Ligand, EA Clark .
CD30 Ligand, P. Romagnani, C. Mavilia and S. Romagnani .
CD27 Ligand, WAM Loenen .
TWEAK, JL Browning, C. Ambrose and C. Hession .
RANK Ligand, WJ Boyle .
APRIL, J. Tschopp .
Apo2L / TRAIL, A. Ashkenazi .
LIGHT, CF Ware .
The IL-6 Family:
IL-6 Ligand and Receptor Family, T. Hirano and T. Fukada .
IL-6, T. Matsuda and T. Hirano .
IL-11, JC Keith Jr. .
Oncostatin M, AG Bruce and TM Rose .
CT-1, KR Chien .
Chronic Inflammatory Mediators:
Cytokines Engaged in Antiviral Action, Macrophage Activation, Angiogenesis, and Regulation of Cell Growth and Differentiation, J. Vilcek .
IFN alpha , IFN beta , and IFN omega Ligands, MS Kunzi and PP Rowe .
IFN gamma , AB and K. Vandenbroeck .
Osteopontin, GJ Nau .
MIF, CN Metz and R. Bucala .
Growth and Angiogenic Factors:
TGF beta , KC Flanders and AB Roberts .
BMP Family, AH Reddi and D. Haudenschild .
PDGF, EW Raines .
VEGF, N. Ferrara .
Poxvirus Vascular Endothelial Growth Factor (VEGF) Homologs of Orf Virus, G. McFadden and R. Moyer .
Angiostatin, AE Papathanassiu, SJ Green, DK Grella and BKL Sim .
Activin, TK Woodruff .
Endostatin, AE Papathanassiu, SJ Green, DK Grella and BKL Sim .
Methoxyestradiol, AE Papathanassiu, SJ Green, DK Grella and BKL Sim .
Poxvirus Growth Factors Related to EGF, G. McFadden and R. Moyer .
Hematopoietic Factors:
Hematopoietic Growth Factors, NA Nicola .
IL-3, JW Schrader .
IL-5, GTF Schwenger, VA Mordvinov, R. Fournier, P. Czabotar, S. Peroni and CJ Sanderson .
Stem Cell Factor, JR Keller and DM Linnekin .
GM-CSF, NA Nicola .
CSF-1, ER Stanley .
G-CSF, S. Nagata .
Erythropoietin, JL Spivak .
Thrombopoietin, DJ Cutter .
CXC Chemokines:
Chemotactic Factors, Neuropeptides, and Other Ligands for Seven Transmembrane Receptors, JJ Oppenheim, OMZ Howard and E. Goetzl .
MGSA / GRO, D. Wang and A. Richmond .
ENA-78, A. Walz .
IL-8, H. Iizasa and K. Matsushima .
GCP-2, A. Wuyts, P. Proost and J. Van Damme .
CTAP-III, beta TG, and NAP-2, E. Brandt, A. Ludwig and H.-D. Flad .
Platelet Factor 4, G. Neufeld, G. Akiri and Z. Vadasz .
IP-10, AD Luster .
MIG, JM Farber .
SDF-1, CR Mackay .
BLR1 Ligand / BCA-1 / BLC, R. Förster .
9E3 / cCAF, M. Martins-Green .
CC, C, and CX3C CHEMOKINES:
MCP-1, MCP-2, MCP-3, MCP-4, and MCP-5, BJ Rollins .
RANTES, TJ Schall and DR Greaves .
I-309, MS Krangel .
MIP- alpha , MIP- beta , B. Sherry and G. Franchin .
Eotaxin, TJ Williams and I. Sabore .
PARC, H. Nomiyama and O. Yoshie .
Eotaxin 2, JR White .
MIP- gamma / MRP-2, B.-S. Youn and BS Kwon .
Mu C10, B.-S. Youn and BS Kwon .
Leukotactin 1, B.-S. Youn and BS Kwon .
CK beta 8-, B.-S. Youn and BS Kwon .
HCC-1, TW Salcedo .
SLC (6CKine), H. Nomiyama and O. Yoshie .
ELC, H. Nomiyama and O. Yoshie .
TECK / CCL25, DJ Catron and A. Zlotnik .
CC Chemokine of Molluscum Contagiosum Virus, G. McFadden and R. Moyer .
Lymphotactin, DJ Catron and A. Zlotnik .
Fractalkine, DR Greaves and TJ Schall .
TARC, O. Yoshie .
Poxvirus Secreted Complement Control Proteins, G. McFadden and R. Moyer .
Related Proinflammatory Factors:
fMLP, F. Boulay, M.-J. Rabiet and M. Tardif .
Lipoxin, BD Levy, CB Clish, K. Gronert and CN Serhan .
Platelet-Activating Factor, PM Henson .
Defensins, T. Ganz .
Leukotriene B4, BK Lam and KF Austen
Neuropeptides and Hormones:
Endorphins, FS Galin and JE Blalock .
alpha- MSH, JM Lipton .
VIP and PACAP, EJ Goetzl, JK Voice and G. Dorsam .
Lysophospholipid Growth Factors, EJ Goetzl, H. Lee and GJ Tigyi .
ACTH, DA Weigent and JE Blalock .
SERP-1, and Secreted Poxviral Serpin, G. McFadden and R. Moyer .
Vaccinia Virus Semaphorin, G. McFadden and R. Moyer .

Volume II:
Immunomodulating Interleukin Receptors:
IL-2 Family Cytokines and their Receptors, WJ Leonard .
IL-2 Receptor, KA Smith .
IL-4 Receptor, AD Keegan .
IL-7 Receptor, H. Spits .
IL-9 Receptor, J.-C. Renauld .
IL-10 Receptor, R. de Waal Malefyt .
IL-12 Receptor, C. Esche, MR Shurin and MT Lotze .
IL-13 Receptor, DJ Matthews and ANJ McKenzie .
IL-15 Receptor, TA Waldmann and Y. Tagaya .
IL-16 Receptor (CD4), DM Center, H. Kornfeld and WW Cruikshank .
IL-17 Receptor, S. Lebecque, F. Fossiez and E. Bates .
Prolactin Receptor, V. Goffin and PA Kelly .
IL-1 Family Receptors:
IL-1 Receptor Family, LAJ O'Neill and SK Dower .
IL-1 Receptor Type I, CA Dinarello .
Poxvirus IL-1 beta Receptor Homologs, G. McFadden and R. Moyer .
IL-18 Receptor, H. Okamura, H. Tsutsui, S.-i. Kashiwamura, T. Yoshimoto and K. Nakanishi .
IL-1 Receptor Type II, CA Dinarello .
TNF Family Receptors:
TNF Receptors, BB Aggarwal, A. Samanta and M. Feldmann .
Poxvirus TNF Receptor Homologs, G. McFadden and R. Moyer .
Lymphotoxin beta Receptor, N. Ruddle and CF Ware .
Fas, S. Nagata .
CD40, EA Clark .
CD30, F. Annunziato, P. Romagnani, C. Mavilia, G. Pizzolo, H. Stein and S. Romagnani .
4-1BB, DS Vinay and BS Kwon .
RANK, WJ Boyle .
Osteoprotegerin, WJ Boyle .
CD27, WAM Loenen .
HVEM, CF Ware .
DR4, DR5, DcR1, DcR2, A. Ashkenazi .
DcR3, A. Ashkenazi .
Ox40, DS Vinay and BS Kwon .
GIT Receptor, DS Vinay and BS Kwon .
IL-6 Family Receptors:
IL-6 Receptor, M. Hibi and T. Hirano .
IL-11 Receptor, J. Keith .
OSM Receptor, TM Rose and AG Bruce .
CT-1 Receptor, KR Chien .
Receptors for Chronic Inflammatory Mediators:
IFN gamma Receptor, V. Shankaran and RD Schreiber .
Poxvirus IFN gamma Receptor Homologs, G. McFadden and R. Moyer .
IFN c beta Receptor, SJ Haque and BRG Williams .
Poxvirus IFN c beta Receptor Homologs, G. McFadden and R. Moyer .
Osteopontin Receptor, GJ Nau .
TGF beta Receptors, P. ten Dijke and C.-H. Heldin .
BMP Receptor, AH Reddi .
Hematopoietic Receptors:.
Hematopoietic Receptor Family, A. Miyajima .
IL-3 Receptor, JW Schrader .
IL-5 Receptor, CJ Bagley, J. Tavernier, JM Woodcock and AF Lopez .
SCF Receptor, D. Linnekin and JR Keller .
GM-CSF Receptor, NA Nicola .
G-CSF Receptor, S. Nagata .
TPO Receptor, DJ Kuter and J. Li .
CXC Chemokine Receptors:
Chemokine Receptors: Overview, PM Murphy .
CXCR1 and CXCR2, I. Roth and C. Hebert .
CXCR3, JM Farber and B. Moser .
CXCR4, B. Moser .
CXCR5, R. Föester .
CC, C, and CX3C CHEMOKINE RECEPTORS:
CCR1, R. Horuk .
CCR2, JM Rodriguez-Frade, M. Mellado and C. Martinez-A .
CCR3, CR Mackay .
CCR4, CA Power .
CCR5, C. Blanpain and M. Parmentier .
CCR6, JM Farber .
CCR7, H. Namiyama and O. Yoshie .
CCR8, M. Napolitano and A. Santoni .
D6, G. Graham and R. Nibbs .
ECRF3, SK Ahuja .
Poxvirus Membrane-bound G Protein-coupled Receptor Homologs, G. McFadden and R. Moyer .
US28, J.-L. Gao .
Kaposi's Sarcoma-associated Herpesvirus GPCR, E. Geras-Raaka and MC Gershengorn .
DARC, R. Horuk .
CX3CR1, T. Imai and O. Yoshie .
Poxvirus Secreted Chemokine-binding Proteins, G. McFadden and R. Moyer .
CCR9, A. Zaballos, J. Gutiérrez, R. Varona and G. Márquez .
XCR1, O. Yoshie .
Miscellaneous Proinflammatory Factor Receptor:
C5a Receptor, TE Hugli and JA Ember .
C3a Receptor, JA Ember and TE Hugli .
PAF Receptors, PM Henson .
fMLP Receptors, F. Boulay, M.-J. Rabiet and M. Tardif .
Opioid mu , delta , and kappa Receptors for Endorphins, DJJ Carr and JE Blalock .
Lipoxin A4 Receptor, N. Chiang, K. Gronert, F.-H. Que and CN Serhan .
ACTH Receptor, FS Galin and JE Blalock
BLTR: the Leukotriene B4 Receptor, AD Luster and AM Tager .
PACAP and VIP Receptors, EJ Goetzl, JK Voice and G. Dorsam .
Lysophospholipid Growth Factor Receptors, EJ Goetzl, S. An and H. Lee .
Appendix.
Abbreviations.
List of Suppliers.
Index.