Caveolae and Lipid Rafts: Roles in Signal Transduction & amp; the Pathogenesis of Human Disease

Caveolae (latin for little caves) are small structures found on the surface of cells. They are responsible for the regulation of important metabolic pathway. As a consequence, they have a role in cancer, cancer, diabetes, and muscular dystrophies. This book analyzes the role and function of caveolae in caveolae / caveolin.

Section 1: Caveolae organization and role in lipid cholesterol metabolism.
Lipid rafts and caveolae organization.
Caveolae and the regulation of cellular cholesterol homeostasis.
Section 2: Caveolae and the regulation of endocytosis.
The Caveolae Internalization Machinery.
Lipid raft mediated entry of bacteria into host cells.
Section 3: Examples of the role of caveolins in cell signaling.
The caveolin interaction with the endothelial nitric oxide synthase (eNOS).
Caveolae and Estrogen Reception Signaling.
eNOS regulation by sphingosine 1-phosphate and caveolin.
Insulin signaling and caveolae.
Section 4: Caveolae and pathologies.
Caveolin-3, Caveolae, and Hereditary Muscle Diseases.
Caveolae and Caveolins in the Vascular System.
Caveolin Proteins in Cardio-pulmonary Disease and Lung Cancers.