Chemokines, Chemokine Receptors and Disease

This volume in the Current Topics in Membranes series discusses the biology of chemokines and their binding partners, chemokine receptors, in normal and disease-related states. Chemokines are small proteins that are important in normal immune responses. Recent research demonstrates a disease, allergy, asthma, and cancer. As a result of the issue of this disease, it is an issue of chemistry. This book presents the topic of chemokines, chemokine receptors, and related pathologies in an integrated manner of knowledge that provides you with a comprehensive and up-to-date knowledge of these topics.

* Provides a comprehensive overview of the history, molecular biology, cell biology, pharmacology, physiology, and pathophysiology of chemokines and their receptors
* Each chapter discusses "future directions and unanswered questions" of chemokine biology
* Serves as a road map for future research

Introduction: Overview and History of Chemokines and Their Receptors.
The Biology CXC Chemokines and Their Receptors.
The Molecular and Cellular Biology of CC Chemokines and Their Receptors.
The Molecular and Cellular Biology of C and CX3C Chemokines and Their Receptors.
Chemokines and Their Receptors in Hematopoietic Cell Development and Function.
Chemokines in Immune Surveillance of the Intestine.
Chemokines and Central Nervous System Physiology.
Chemokines and Chemokine Receptors in Pulmonary Disease.
Chemokines, Chemokine Receptors and Atherosclerosis.
CXC Chemokines in Cancer.
Chemokines and Chemokine Receptors in Infectious Disease.
New Therapies Targeting Chemokine Receptors: Can Changing the Way Cells Traffic Be Used to Treat Human Disease?