Medicinal Chemistry of Anticancer Drugs

Antitumour chemotherapy is nowadays a very important source of information. I do not know how to treat chemistry and drug design. Cytotoxic chemotherapy is gradually replicated in cancer cells. These therapies are in their infancy, but they have to be effective with therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Antibiotic Drugs and Biochemical Reactor of Antiviral Drugs drugs, which would allow the design of new active structures.

* Presents information in a clear and concise way
Historical background provides insights on the anticancer field
* Extensive references to primary literature

1. Introduction to anticancer chemotherapy
2. Antimetabolites
3. Anticancer drugs that inhibit hormone action
4. Anticancer drugs acting via radical species. Photosensitizers and photodynamic therapy of cancer.
5. DNA alkylating agents
6. Alkylating and non-alkalating drugs interacting with the DNA minor groove.
7. DNA intercalation and inhibition of topoisomerases
8. Anticancer drugs targeting tubulin and microtubules
9. Drugs targeting signaling pathways for tumour cell growth and proliferation
10.Other approaches to targeted therapy
11.Drug targeting in anticancer chemotherapy
12.Resistance to antitumour agents and drugs that modulate it
13. Chemoprevention carcinoma