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HPLC Method Development for Pharmaceuticals
ID: 172955
Satinder Ahuja, Henrik Rasmussen
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High pressure, or high performance, liquid chromatography (HPLC) is a method of choice for monitoring, testing and assimilation. . HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC. Includes a review and update of the current state of the art and science of HPLC, including chemistry, methods of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on a pharmaceutical perspective.
HPLC Method Development for Pharmaceuticals is a new method of analysis for experts in the pharmaceutical industry.
* Covers the requirements for the use of HPLC in a pharmaceutical laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development
1. Overview (Satinder Ahuja).
2. HPLC Theory (YV Kazakevich).
3. HPLC Columns and Packings (UD Neue et al .).
4. Column Characterization and Selection (D. Visky).
5. Chiral Separations (Xiande Wang et al .).
6. Contemporary Liquid Chromatographic Systems for Method Development (M. Swartz).
7. Hyphenated Techniques (DL Norwood et al .).
8. HPLC Sample Preparation (G. Slack, NH Snow).
9. Instrument and Software Qualification and Validation (D. Van Geel).
10. Pharmaceutical Development: From Pre-clinical to Post Approval (K. Bynum).
11. HPLC Method Development for Drug Discovery. LC-MS Assays in Rapid PK Applications (Xiaoying Xu, W. Korfmacher).
12. HPLC Method Development in Early Phase Pharmaceutical Development (HT Rasmussen et al .).
13. HPLC Method Development in Late Phase Pharmaceutical Development (M.Ilias Jimidar).
14. Use of HPLC for In-process Testing (C. Richardson).
15. Method Development for Biomolecules (DE Raynie, JL Driver).
16. Method Validation (M. Ilias Jimidar et al .).
17. Troubleshooting HPLC Methods (H. McNair).
18. Molecularly Imprinted Polymers as Sorbents for Separations and Extractions (MT Koesdjojo et al .).
HPLC Method Development for Pharmaceuticals is a new method of analysis for experts in the pharmaceutical industry.
* Covers the requirements for the use of HPLC in a pharmaceutical laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development
1. Overview (Satinder Ahuja).
2. HPLC Theory (YV Kazakevich).
3. HPLC Columns and Packings (UD Neue et al .).
4. Column Characterization and Selection (D. Visky).
5. Chiral Separations (Xiande Wang et al .).
6. Contemporary Liquid Chromatographic Systems for Method Development (M. Swartz).
7. Hyphenated Techniques (DL Norwood et al .).
8. HPLC Sample Preparation (G. Slack, NH Snow).
9. Instrument and Software Qualification and Validation (D. Van Geel).
10. Pharmaceutical Development: From Pre-clinical to Post Approval (K. Bynum).
11. HPLC Method Development for Drug Discovery. LC-MS Assays in Rapid PK Applications (Xiaoying Xu, W. Korfmacher).
12. HPLC Method Development in Early Phase Pharmaceutical Development (HT Rasmussen et al .).
13. HPLC Method Development in Late Phase Pharmaceutical Development (M.Ilias Jimidar).
14. Use of HPLC for In-process Testing (C. Richardson).
15. Method Development for Biomolecules (DE Raynie, JL Driver).
16. Method Validation (M. Ilias Jimidar et al .).
17. Troubleshooting HPLC Methods (H. McNair).
18. Molecularly Imprinted Polymers as Sorbents for Separations and Extractions (MT Koesdjojo et al .).
172955
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Satinder Ahuja, Henrik Rasmussen