Carbohydrate Chemistry, Biology and Medical Applications

The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone to the elucidation of stereochemistry of carbohydrates. The carbohydrates and glycoproteins and proteoglycans have been found to be unconventional in their basic structure, biosynthesis, immunology, functions, and clinical uses.
The chapters in this book and the logical sequence of carbohydrates as well as biochemistry of carbohydrates.
This book offers a detailed panoramic view of chemists, biologists and health professionals. Each chapter is authored by contributors.


Preface
Contributors list
1. The Development of Carbohydrate Chemistry and Biology (D. Horton)
2. Carbohydrate Structure Determination by Mass Spectrometry (B. Xie and CE Costello)
3. Chemical Synthesis of Complex Carbohydrates (Z. Guo)
4. Enzymatic Synthesis of Oligosaccharides and Conversion to Glycolipids (DM Su, H. Eguchi, C. Xia, J. Song, W. Yi, RL Woodward and PG Wang)
5. Proteoglycans in the Lung (MS Ludwig)
6. Proteoglycans of the Intervertebral Disc (PJ Roughley)
7. Small Leucine Rich-Repeat Proteoglycans of Skin (PG Scott)
8. Functional Glycosaminoglycans in the Eye (M. Zako and M. Yoneda)
9. Biological Function of Glycosaminoglycan (M. Roth, E. Papakonstantinou and G. Karakiulakis)
10. Physiological, Pathophysical and Therapeutic Roles of Heparin / Heparan Sulfate (J. Xie, S. Murugesan and RJ Linhardt)
11. Carbohydrates and Cutaneous Wound Healing (A. Burd and L. Huang)
12. Carbohydrates in Human Milk and Infant Formulas (G. Boehm, B. Stahl, J. Knol and J. Garssen)
13. Role of Cell Surface Carbohydrates in Development and Disease (MN Fukuda, TO Akama and K. Sugihara)
14. Therapeutic Use of Hyaluronan-Based Derived Products (EA Balazs and PA Band)
15. Drug Delivery and Medical Applications of Chemically Modified Hyaluronan (LZ Avila, DA Gianolio, PA Konowicz, M. Philbrook, MR Santos and RJ Miller)
16. Carbohydrate Microarrays as Essential Tools of Postgenomic Medicine (X. Zhou, GT Carroll, C. Turchi and D. Wang)
17. Carbohydrate Arrays for Basic Science and as Diagnostic Tools (T. Horlacher, JL de Paz and PH Seeberger)
Subject Index