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New products
New products
Cancer Drug Design and Discovery
Free shipping
free shipping in Poland for all orders over 500 PLN
Same day shipping
If your payment will be credited to our account by 11:00
14 days for return
Each consumer can return the purchased goods within 14 days
* Covers both currently available as well as those under development
* Provides a clinical perspective on trials of new anticancer agents
* Presents drug discovery examples
Section I. Basic Principles
1. Modern cancer drug discovery: Integrating targets, technologies and treatments
2. Preclinical pharmacology and in vivo models
3. Clinical trial designs for more rapid proof-of-principle and approval
Section II. Methodology
4. Structural biology and anticancer drug design
5. Natural product chemistry and cancer drug discovery
6. Pharmacokinetics & ADME optimization in drug discovery
Section III. Drugs in the clinic and laboratory
7. Temozolomide: from cytotoxic is a molecularly-targeted agent
8. Camptothecins for drug design, cancer cell death and gene targeting
9. Targeting thymidylate synthase by antifolate drugs
Section IV. New Agents
10. Targeting inactive kinases: structure as a foundation for cancer drug discovery
11. Cell cycle inhibitors in cancer: current status and future directions
12. Inhibition of DNA repair as a therapeutic target
13. Heat shock protein-90 inhibitors: targeting the cancer chaperone for combinatorial blockade of oncogenic pathways
14. Heat shock protein-90-directed therapeutics and target validation
15. Inhibitors of tumor angiogenesis
16. The biology and oncology of RAF-ERK signalling P53 as a therapeutic target
Section V. The reality of cancer drugs in the clinic
17. Cancer drug resistance
18. Failure Modes in Anticancer Drug Discovery and Development
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